Free Shipping

on orders over $25

0 item(s) | $0 View Cart

List Price: $29.60

Our Price: $25.16 You Save: $4.44 (15%)

Free Shipping

SAMe - 30 Tablets

Image may differ in size, form, flavor, or label.

SAMe

30 Tablets
  • Item #: 9246

Orders Placed by 4:00 PM EST

Ship the Same Day |

List Price: $29.60

Our Price: $25.16 You Save: $4.44 (15%)


Add to Wishlist

SAMe

S-Adenosyl-L-Methionine (SAMe) has several critical physiological functions and is the common thread between three key metabolic pathways. Well-recognized as a unique methyl donor for numerous biological reactions, including DNA methylation, it also links methylation to polyamine synthesis (necessary for cell survival and growth), and trans sulfuration, which is responsible for cysteine production, the rate-limiting factor in glutathione synthesis. Its unique positioning within these intersecting pathways explain its role as a regulator of redox status, cellular metabolism, proliferation and apoptosis.

Clinically it has proven beneficial for a number of conditions, most notably osteoarthritis, neurodegenerative disease, depression and liver disease.5 For patients with major depressive disorder, SAMe has been shown to be effective not only when compared to standard antidepressants, but also for selective serotonin reuptake inhibitor (SSRI) nonresponders.6,7 SAMe has also shown efficacy for osteoarthritis comparable to NSAIDs, including celecoxib.8,9 Quite importantly, it is likely via increases in cartilage formation, glutathione production, DNA methylation and gene expression which contribute to its efficacy, a stark contrast from pharmaceutical analgesics.10 Research also suggests benefit for neurodegenerative disease, and potentially for improving endothelial function.

  • Key factor in several key biological pathways, including methylation reactions, glutathione formation and glutathione-s-transferase activity
  • Complexed with disulfate tosylate, a well-tolerated, stable and clinically tested form
  • Enteric coating protects SAMe degradation from gastric acid, allowing for significantly improved intestinal absorption
  • 200 mg SAMe per tablet, allows for flexible dose titration
  • Sourced from the highest quality Italian Isoactive SAMe available on the market
  • Isoactive SAMe uses a natural fermentation process that yields 40% higher active ingredients over synthetic variations<;li>
  • Suitable for vegetarians/vegans

SAMe 30 Tablets by Bioclinic Naturals

Supplement Facts
Serving Size: 1 Tablet
Servings per Container: 30

  Amount per Serving

S-Adenosyl-L-Methionine (SAMe) 200 mg

Other ingredients: Microcrystalline cellulose, mannitol, enteric coating (methacrylic acid copolymer, talc, triethyl citrate, glyceryl palmitostearate, silica, titanium dioxide, medium chain triglycerides, yellow iron oxide), glyceryl behenate, vegetable grade magnesium stearate (lubricant), silica, sodium starch glycolate.

Recommended Adult Dose: SAMe should always be taken on an empty stomach.
For mood balance: 1–4 tablets 2 times per day or as directed by a health care practitioner.
For osteoarthritic pain: 1–3 tablets 2 times per day or as directed by a health care practitioner. Do not exceed a total of 8 tablets per day. SAMe must be taken for a minimum of 2 weeks, at which time effects should be observed.

This product is not available in any additional sizes, forms, or flavors.

There are currently no reviews for this product.

Review This Product

The statements and claims made on this site have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Accutrition Nutritional Consultants® is not liable for the misuse or misinterpretation of any information on this site. Product ingredients and formulations may change over time. We attempt to keep this information up-to-date and accurate, but it is your responsibility to review all product labels before opening. Always consult with your health care practitioner before implementing a diet or supplement regimen.