Free Shipping

on orders over $25

0 item(s) | $0 View Cart

List Price: $26.00

Our Price: $22.10 You Save: $3.90 (15%)

DGL - 180 chewables

Image may differ in size, form, flavor, or label.

DGL

180 Chewables
  • Item #: 9227

Orders Placed by 4:00 PM EST

Ship the Same Day |

List Price: $26.00

Our Price: $22.10 You Save: $3.90 (15%)


Add to Wishlist

Deglycyrrhizinated licorice, or DGL, has been used clinically for decades, primarily for the treatment of peptic ulcers. Licorice has been shown to inhibit several inflammatory enzymes, including both cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), decreasing the production of several potent inflammatory compounds, including prostaglandin E2, thromboxane B2, and leukotriene B4. Importantly, this inhibition is not due to glycyrrhizic acid, the component of licorice which has been removed in DGL, and which is associated with mineralocorticoid excess and hypertension. Another component of licorice, glabridin, has been shown to prevent lipopolysaccharide (LPS) induced production of inflammatory compounds, including nitric oxide and interleukin-1 beta, whereas glycyrrhizic acid has no effect.

Clinically, DGL has been shown to have comparable efficacy to cimetidine for both the healing and prevention of ulcer recurrences. Additionally, extracts of licorice have been shown to inhibit the adhesion of H. pylori to gastric mucosa, as well as the growth of antibiotic resistant strains, suggesting multiple mechanisms of action for its anti-ulcer benefit. The use of chewable tablets appears necessary for DGL’s efficacy, as it allows for distribution and absorption by the gastric mucosa.

  • DGL chewable tablets is the form associated with the greatest clinical efficacy, as it allows for licorice to be released in the stomach and dispersed/absorbed by the gastric mucosa
  • Provides 400 mg DGL per tablet, the clinically effective dosage
  • Deglycyrrhizination prevents adverse effects associated with licorice consumption
  • Pleasant tasting tablets for better compliance

DGL - Supplement Facts

Suggested Use: Chew 1 tablet per day 20 minutes before each meal or as directed by a health care professional. Consult a health care professional for use beyond 16 weeks.

Contraindications: Nearly all contraindications to DGL are due to pseudohyperaldosteronism or mineralocorticoid excess, effects which appear to be primarily due to glycyrrhizic acid. Although there are no apparent contraindications for DGL, patients with hypertension, congestive heart failure and hypokalemia should be monitored carefully. The safety of DGL in pregnancy and breastfeeding is unknown and should be used with caution. Consult a health care professional if you experience persistent stomach or gastrointestinal upset. Keep out of reach of children.

There are currently no reviews for this product.

Review This Product

The statements and claims made on this site have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Accutrition Nutritional Consultants® is not liable for the misuse or misinterpretation of any information on this site. Product ingredients and formulations may change over time. We attempt to keep this information up-to-date and accurate, but it is your responsibility to review all product labels before opening. Always consult with your health care practitioner before implementing a diet or supplement regimen.